Publications

38. Garren H, Robinson W, Krasulová E, Havrdová E, Nadj C, Selmaj K, Losy J, Nadj I, Radue EW, Kidd BA, Gianettoni J, Tersini K, Utz PJ, Valone F, Steinman L and the BHT-3009 Study Group. Phase 2b Trial of a DNA Vaccine Encoding Myelin Basic Protein in Relapsing Multiple Sclerosis. Annals of Neurology, in press.

37. Han MH, Hwang S, Roy DB, Lundgren DH, Price JV, Ousman S, Fernald G, Gerlitz B, Robinson WH, Baranzini SE, Grinnell BW, Raine CS, Sobel RA, Han DK, and Steinman L. Proteomic Analysis of Active Multiple Sclerosis Lesions Reveals Therapeutic Targets.  Nature, 451:1076-1081, 2008. doi:10.1038/nature06559

36. Ray S, Britschgi M, Herbert C, Takeda-Uchimura Y, Boxer A, Blennow K, Friedman LF, Galasko DR, Jutel M, Karydas A, Kaye JA, Leszek J, Miller BL, Minthon L, Quinn JF, Rabinovici GD, Robinson WH, Sabbagh MN, So YT, Sparks DL, Tabaton M, Tinklenberg J, Yesavage JA, Tibshirani R, Wyss-Coray T. Classification and Prediction of Clinical Alzheimer's Diagnosis Based on Plasma Signaling Proteins. Nature Medicine. 13(11):1359-62, 2007

35. Bar-Or A, Vollmer T, Antel J, Arnold DL,Bodner CA, Campagnolo D, Gianettoni J, Jalili F,Kachuck N, Lapierre Y, Niino M, Oger J, Price M, Rhodes S, Robinson WH, Shi F-D, Utz PJ, Valone F, Weiner L, Steinman L, Garren H. Induction of Antigen-Specific Tolerance in Multiple Sclerosis After Immunization With DNA Encoding Myelin Basic Protein in a Randomized, Placebo-Controlled Phase 1/2 Trial. Arch. Neurol. 2007; 64:E1-E9.

34. Ousman, SS, Tomooka, BH, van Noort JM, Wawrousek EF, O’Connor KC, Hafler DA, Sobel RA, Robinson WH, Steinman L. Protective and Therapeutic Role for αΒ-crystallin in Autoimmune Demyelination. Nature. 2007; 448:474-479.

33. Elchuri S, Naeemuddin M, Sharpe O, Robinson WH, Huang TT. Identification of Biomarkers Associated with the Development of Hepatocellular Carcinoma in CuZn Superoxide Dismutase Deficient Mice. Proteomics. 2007; 7:2121-2129.

32. Paniagua PT, Robinson WH. Imatinib for the Treatment of Rheumatic Diseases. Nature Clinical Practice Rheumatology. 2007:190.191.

31. O’Connor KC, McLaughlin KA, De Jager PL, Chitnis T, Bettelli E, Xu C, Robinson WH, Cherry SV, Bar-Or A, Banwell B, Fukaura H, Fukazawa T, Tenembaum S, Wong SJ, Tavakoli NP, Idrissova Z, Viglietta V, Rostasy K, Pohl D, Dale RC, Freedman M, Steinman L, Buckle GJ, Kuchroo VK, Hafle DA, Wucherpfennik KW. Self-antigen Tetramers Discriminate Between Myelin Autoantibodies to Native or Denatured Protein. Nature Medicine. 2007; 13:211-217.

30. Hueber, W, Tomooka, BH, Zhao, X, Kidd, BA, Drijfhout, JW, Fries, JF, van Venrooij, WJ, Metzger, AL, Genovese, MC, Robinson, WH. Proteomic Analysis of Secreted Proteins in Early Rheumatoid Arthritis: Anti-citrulline Autoreactivity is Associated With up Regulation of Proinflammatory Cytokines. Ann Rheum Dis. 2007;66:712–719.

29. Ho PP, Higgins JP, Kidd BA, Tomooka B, Digennaro C, Lee LY, de Vegvar HE, Steinman L, Robinson WH.  Tolerizing DNA Vaccines for Autoimmune Arthritis.  Autoimmunity. 39:675-82, 2006.

28. Lopez-Avila V, Sharpe O, Robinson WH. Determination of Ceruloplasmin in Human Serum by SEC-ICPMS. Anal Bioanal Chem. 2006;386:180-187.

27. Paniagua RT, Sharpe O, Ho PP, Chan SM, Chang A, Higgins JP, Tomooka BH, Thomas FM, Song JJ, Goodman SB, Lee DM, Genovese MC, Utz PJ, Steinman L, Robinson WH. .   Selective Tyrosine Kinase Inhibition by Imatinib Mesylate for the Treatment of Autoimmune Arthritis.  J Clin Invest. 2006; 116:2633-2642.

26. Hueber W, Robinson WH. Proteomic Biomarkers for Autoimmune Disease. Proteomics. 2006; 6:4100-4105.

25. Kuhn, KA, Lulik L, Tomooka B, Brashler KJ, Arend WP, Robinson WH, Holers VM. Antibodies Against Citrullinated Proteins Enhance Tissue Injury in Experimental Autoimmune Arthritis. J. Clin. Invest. 2006;116:961-73.

24. Robinson, WH. Antigen Arrays for Antibody Profiling, Curr. Opin. Chem. Biol. 2006;10:67-72.

23. Kanter JL, Narayana S, Ho PP, Catz I, Warren KG, Sobel RA, Steinman L, Robinson WH. Lipid Microarrays Identify Key Mediators of Autoimmune Brain Inflammation. Nat. Med. 2006;12:138-143.

22. Steinman L, Utz PJ, Robinson WH. Suppression of Autoimmunity via Microbial Mimics of Altered Peptide Ligands. Curr Top Microbiol Immunol. 2005;296:55-63.

21. Platten M, Ho PP, Youssef S, Fontoura P, Garren H, Hur EM, Gupta R, Lee LY, Kidd BA, Robinson WH, Sobel RA, Selley ML, Steinman L. Treatment of Autoimmune Neuroinflammation With a Synthetic Tryptophan Metabolite. Science. 2005, 310:850-5.

20. Ho PP, Fontoura P, Platten M, Sobel RA, DeVoss JJ, Lee LY, Kidd BA, Tomooka BH, Capers J, Agrawal A, Gupta R, Zernik J, Yee MK, Lee BJ, Garren H, Robinson WH, Steinman L. A Suppressive Oligodeoxynucleotide Enhances the Efficacy of Myelin Cocktail/IL-4-Tolerizing DNA Vaccination and Treats Autoimmune Disease. J Immunol. 2005, 175(9):6226-34.

19. Utz PJ, Steinman L, and Robinson WH.  Protein Microarrays for Analysis of Antibody Responses in Animals and Humans.  In Protein Microarrays, Chapter 19, pgs. 365-376, Edited by Michael Schena, Jones and Bartlett, Sudbury, MA 2005 

18. Vossenaar ER, Robinson WH. Citrullination and Autoimmune Disease: 8th Bertine Koperberg Meeting. Ann Rheum Dis. 2005, 64(10):1513-5.

17. Hueber W, Kidd BA, Tomooka BH, Lee BJ, Bruce B, Fries JF, Sonderstrup G, Monach P, Drijfhout JW, van Venrooij WJ, Utz PJ, Genovese MC, Robinson WH. Antigen Microarray Profiling of Autoantibodies in Rheumatoid Arthritis. Arthritis Rheum. 2005, 52(9):2645-55.

16. Fontoura P, Ho PP, DeVoss J, Zheng B, Lee BJ, Kidd BA, Garren H, Sobel RA, Robinson WH, Tessier-Lavigne M, Steinman L. Immunity to the Extracellular Domain of Nogo-A modulates Experimental Autoimmune Encephalomyelitis. J Immunol. 2004 Dec 1;173(11):6981-92.

15. Magnano MD, Robinson WH, Genovese, MC. Demyelination and Inhibition of Tumor Necrosis Factor (TNF). Clinical and Experimental Rheumatology. 2004. S134-S140.

14. Graham KL, Robinson WH, Steinman L, Utz PJ. High-throughput Methods for Measuring Autoantibodies in Systemic Lupus Erythematosus and Other Autoimmune Diseases. Autoimmunity. 2004, 37(4):269-72. Review.

13. Hueber W, Zeng D, Sharpe O, Robinson WH, Strober S, Utz PJ. Characterization of Novel Antigens Recognized by Serum Autoantibodies from Anti-CD1 TCR-transgenic Lupus Mice. Eur J Immunol. 2004, 34(6): 1654-62.

12. Neuman De Vegvar HE, Robinson WH. Microarray Profiling of Antiviral Antibodies for the Development of Diagnostics, Vaccines, and Therapeutics. Clin Immunol. 2004, 111(2):196-201.

11. Utz PJ, Genovese MC, Robinson WH. Unlocking the "PAD" Lock on Rheumatoid Arthritis. Ann Rheum Dis. 2004, 63(4):330-2

10. Hueber W, Utz PJ, Robinson WH. Autoantibodies in Early Arthritis: Advances in Diagnosis and Prognostication. Clin Exp Rheumatol. 2003, 21(5 Suppl 21): S59-64. Review.

9. Robinson WH, Utz PJ, Steinman L. Genomic and Proteomic Analysis of Multiple Sclerosis. Opinion. Curr Opin Immunol. 2003, 15(6):660-7.

8. Robinson WH, Steinman L, Utz PJ. Protein Arrays for Autoantibody Profiling and Fine-Specificity Mapping. Proteomics. 2003, 3(11):2077-84.

7. Neuman De Vegvar HE, Amara RR, Steinman L, Utz PJ, Robinson HL, Robinson WH. Microarray Profiling of Antibody Responses Against Simian-Human Immunodeficiency Virus: Postchallenge Convergence of Reactivities Independent of Host Histocompatibility Type and Vaccine Regimen. J Virol. 2003, 15;77(20):11125-11138.

6. Robinson WH, Fontoura P, Lee BJ, De Vegvar HE, Tom J, Pedotti R, DiGennaro CD, Mitchell DJ, Fong D, Ho PP, Ruiz PJ, Maverakis E, Stevens DB, Bernard CC, Martin R, Kuchroo VK, Van Noort JM, Genain CP, Amor S, Olsson T, Utz PJ, Garren H, Steinman L. Protein Microarrays Guide Tolerizing DNA Vaccine Treatment of Autoimmune Encephalomyelitis. Nat Biotechnol. 2003, 21(9):1033-1039

5. Robinson WH, DiGennaro C, Hueber W, Haab B, Kamachi M, Dean E, Fournel S, Fong D, Genovese MC, de Vegvar H, Steiner G, Hirschberg D, Muller S, Pruijn G, van Venrooij W, Smolen J, Brown P, Steinman L, Utz P.  Antigen Arrays for Multiplex Characterization of Autoantibody Responses.  Nature Medicine, 8:295-301, 2002

4. Robinson WH, Steinman L, Utz PJ. Protein and Peptide Array Analysis of Autoimmune Disease. Biotechniques. 2002, Suppl:66-9. Review.

3. Hueber W, Utz PJ, Steinman L, Robinson WH. Autoantibody Profiling for the Study and Treatment of Autoimmune Disease. Arthritis Res. 2002, 4(5):290-5. Review.

2. Robinson WH, Steinman L, Utz PJ. Proteomics Technologies for the Study of Autoimmune Disease. Arthritis Rheum. 2002, 46(4):885-93.

1. Robinson WH, Garren H, Utz PJ, Steinman L. Millennium Award. Proteomics for the Development of DNA Tolerizing Vaccines to Treat Autoimmune Disease. Clin Immunol. 2002, 103(1):7-12. Review.